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Principles of Medicine in Africa

Principles of Medicine in Africa

Principles of Medicine in Africa

Edition:
5th Edition
Editors:
David Mabey, London School of Hygiene and Tropical Medicine
Martin W. Weber, World Health Organization
Moffat Nyirenda, London School of Hygiene and Tropical Medicine
Dorothy Yeboah-Manu, Noguchi Memorial Institute for Medical Research, University of Ghana
Jackson Orem, Uganda Cancer Institute, Kampala
Laura Benjamin, University College London
Michael Marks, London School of Hygiene and Tropical Medicine
Nicholas A. Feasey, Liverpool School of Tropical Medicine
Yayehyirad Kitaw, Mitike Molla, Gail Davey, Eldryd Parry, Helen Nabwera, Modou Jobe, Andrew M. Prentice, Nathan Post, Kiran Jobanputra, Bern-Thomas Nyang'wa, Bukola Elizabeth Oluyide, Robert Onus, Bhargavi Rao, Heiner Grosskurth, Benson Droti, Juliet Nabyonga, Jean Baptiste Nikiema, Ruairi Brugha, Derrick Muneene, Tim Baker, Ben Morton, Karima Khalid, Mtisunge Kachingwe, Trustworthy Majuta, Camilla Buchanan, Peter Olute Okoth, Amha Achamyelew Yigzaw, Fabio Uxa, Helenlouise Taylor, Venice Omona, Giorgio Tamburlini, Anne J. Rerimoi, Ayo Palmer, E. Kim Mulholland, Martin W. Weber, Samuel Akech, Steve Collins, Marko Kerac, James A. Berkley, Bridget Freyne, Watipaso Wanda, Jenala Njirammadzi, Melita Gordon, Ambrose Agweyu, Heather Zar, Oghenebrume Wariri, Lien Anh Ha Do, Assan Jaye, Hilton C. Whittle, Rudzani Muloiwa, Gyaviira Nkurunungi, Gift Ahimbisibwe, Stephen Cose, Heidi Hopkins, Joaniter I. Nankabirwa, David Mabey, Christopher J. M. Whitty, Bayodé Roméo, Priscilla Haguma, Emmanuel Nsutebu, Sharon Nyesiga, Jamie Rylance, Shevin Jacob, Rodgers Ayebare, Daniel Bulwadda, Mohammed Lamorde, Titus Divala, Sam Ghebrehewet, Peter MacPherson, Sarah Staedke, Joaniter Nankabirwa, Arthur Mpimbaza, Abel Kakuru, Nyasha Veronica Dzavakwa, Sara Lowe, Rashida Ferrand, Linda Boloko, David Barr, Sean Wasserman, Charlotte Schutz, Graeme Meintjes, Stephen Gordon, Dingase Dula, Johnstone Kumwenda, Olubukola T. Idoko, Philippe Mayaud, Daniel J. McCartney, Francis J. Ndowa, David C. W. Mabey, Priyanka Patel, Esmeda Chirwa, Agness Lakudzala, Tom Parks, Frieder Schaumburg, Soumeya Ouangraoua, Mouhamadou Abdoulaye Sonko, Matthew P. Rubach, Elichilia R. Shao, Venance P. Maro, John Crump, Michael J. Maze, Georgies F. Mgode, Kajiru Kilonzo, John Crump, Geraint R. Davies, Robin Bailey, Richard Kock, Abdinasir Yusuf Osman, Leonard Mboera, Richard Idro, Charles R. Newton, Derek J. Sloan, Stellah G. Mpagama, Saba M. Lambert, Steve L. Walker, Richard Odame Phillips, Yaw Ampem Amoako, Samuel Duodu, Gloria Ansa, Japheth A. Opintan, Japheth A. Opintan, Appiah-Korang Labi, Noah Obeng-Nkrumah, Antoinette Bediako-Bowan, Emma Thompson, Catherine Houlihan, Naomi Walker, Stella Atim, Izabela Mauricio de Rezende, Derick Kimathi, George M. Warimwe, A. Desiree LaBeaud, Oyewale Tomori, Betty S. Apica, Geraldine A. O'Hara, Jolynne Mokaya , George M. Warimwe, Marieke Cornelia Johanna Dekker, Elichilia Robert Shao, Sarah Japhet Urasa, William Patrick Howlett, Nginache Nampota-Nkomba, Antonia Ho, Pascal Mkanda, Andrew Hall, Colin S. Brown, Olusola Aruna, Adesola Yinka-Ogunleye, Lance Turtle, Michael Abouyannis, Mainga Hamaluba, Michael Abouyannis, Mainga Hamaluba, Titus Divala, Michael Marks, Antonia Ho, Eduard Zijlstra, Ahmed M. Musa, Janelisa Musaya, Peter Nambala, Westain Tizgo Nyirenda, Julius Mulindwa, Eduard Zijlstra, Paul Kelly, Humphrey Mazigo, Michael Brown, Simon J Brooker, Stella Kepha, Amaya Bustinduy, Sekeleghe Kayuni, Ana Olga Mocumbi, Camilla Rothe, Linda B. Debrah, Samuel Wanji, Inge Kroidl, Michele Esther Murdoch, Ian Elliot Murdoch, Ewan Hunter, Sarah Urasa, Laura Nabarro, Karima Achour, Camilla Rothe, Clare E. Warrell, Anna M. Checkley, Chris Bodimeade, Rita Oladele, Olusola Ayanlowo, Bright Ocansey, Neil R. H. Stone, Yoseph Mamo, Andrew Mortimore, David I. W. Phillips, Jean Claude N. Mbanya, Camille M. Mba, Andrew E. Uloko, Roberta Lamptey, Geoffrey V. Gill, Richard W Walker, Matthew L. Davies, Kathleen Bateman, Tamara Phiri, Myles Connor, Alan Bryer, Laura Benjamin, Thembi Katangwe, Tiwonge Phiri, Macpherson Mallewa, Primrose Nyamayaro , Clement Nhunzvi, Rukudzo Mwamuka, Awoke Mihretu, Dixon Chibanda, Rebecca Nantanda, Duncan G. Fullerton, Kevin Mortimer, Refiloe Masekela, Brian Allwood, Stephen B. Gordon, Jeremiah Chakaya, Chris Lavy, Tracey Smythe, Debra Mudariki, Charles Kiiza Mondo , Juergen Freers, Twalib Aliku, Zhang Wanzhu, John G. Kellett, Jamie Rylance, Bruce Kirenga, I
Published:
June 2025
Availability:
Available
Format:
Hardback
ISBN:
9781316511435

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£230.00
GBP
Hardback
$299.00 USD
eBook

    Principles of Medicine in Africa combines clinical medicine with a rich understanding of the major environmental and cultural influences on health and disease, providing comprehensive guidance for anyone intending to practise medicine in Africa. Presenting disease in the context of family and culture, the effects of inequality and problems of limited resources are addressed. The authors have a wealth of experience in front line healthcare in Africa and provide practical, evidence-based management guidelines for all the common and less common conditions likely to be encountered. This fifth edition has been thoroughly updated to incorporate the latest research findings and management guidelines and there has been much greater involvement of African physicians in the writing and editorial process. The chapters on cancer and non-communicable diseases have been expanded and new chapters have been added on digital health, critical care in a resource-limited setting, antimicrobial resistance, COVID-19 and other emerging infectious diseases.

    • Focuses on the unique aspects of clinical practice in Africa, incorporating important geographical and cultural context to the problems faced by patients and clinicians
    • Featuring over 600 high-quality colour clinical images and illustrations throughout, aiding readers in their understanding of how to diagnose and manage the diseases discussed
    • Authors have a wealth of experience in frontline healthcare and provide practical, evidence-based management guidelines for all the common and less common conditions likely to be encountered

    Product details

    June 2025
    Hardback
    9781316511435
    1120 pages
    285 × 223 × 58 mm
    3.29kg
    Available

    Table of Contents

    • Part I. Health and Disease:
    • 1. People and the environment
    • 2. Food and nutrition
    • 3. Humanitarian crises and forced displacement
    • 4. Managing a health service with management and financing of drug supply
    • 5. Digital health
    • 6. Critical care medicine
    • Part II. Mother and Child Health:
    • 7. The pregnant patient
    • 8. Neonatal care
    • 9. The integrated management of childhood illness (IMCI)
    • 10. Severe acute malnutrition in childhood
    • 11. Diarrhoea
    • 12. Pneumonia and other acute lower respiratory tract infections in children
    • 13. Measles
    • 14. Pertussis
    • Part III. Infection: General Principles:
    • 15. Immune response to infections
    • 16. Approach to the febrile adult patient
    • 17. Management of Sepsis
    • 18. Infection prevention and control
    • 19. Outbreaks and epidemics
    • Part IV. Major Common Infections:
    • 20. Malaria
    • 21. HIV/AIDS
    • 22. Tuberculosis
    • 23. Pneumonia in adults
    • 24. Meningitis
    • 25. Sexually transmitted infections
    • Part V. Bacterial Infections:
    • 26. Typhoid, paratyphoid and non-typhoid Salmonella infections
    • 27. Streptococcus pyogenes and Staphylococcus aureus
    • 28. Rickettsioses and other rickettsial disease
    • 29. Brucellosis
    • 30. Leptospirosis
    • 31. Relapsing fever
    • 32. Plague
    • 33. Anthrax
    • 34. Tetanus
    • 35. Diptheria
    • 36. Leprosy
    • 37. Mycobacterium ulcerans Disease (Buruli ulcer)
    • 38. Cholera
    • 39. Antimicrobial resistance
    • Part VI. Viral Infections:
    • 40. Viral haemorrhagic fevers: lassa fever, rift valley fever, ebola/marburg fever and crimean–congo fever
    • 41. Yellow fever
    • 42. Hepatitis
    • 43. Dengue
    • 44. Rabies
    • 45. Influenza
    • 46. Poliomyelitis
    • 47. Varicella (chickenpox), herpes zoster and monkeypox
    • 48. Rubella
    • 49. Mumps
    • 50. Covid-19
    • Part VII. Protozoal Infections:
    • 51. Leishmaniasis
    • 52. Human African trypanosomiasis
    • 53. Amoebiasis
    • 54. Intestinal protozoa
    • Part VIII. Helminth Infections:
    • 55. Intestinal helminths
    • 56. Schistosomiasis
    • 57. Lymphatic filariasis and loa loa
    • 58. Onchocerciasis
    • 59. Cysticercosis and neurocysticercosis
    • 60. Hydatid disease
    • 61. Paragonimiasis
    • 62. Trichinellosis
    • 63. Guinea Worm
    • Part IX. Fungal Infections:
    • 64. Fungal infections
    • Part X. Non-Communicable Diseases:
    • 65. Chronic and non-communicable disease in Africa
    • 66. Diabetes mellitus
    • 67. Hypertension
    • 68. Stroke
    • 69. Epilepsy
    • 70. Mental health: depression, post-traumatic stress disorder, substance misuse and stigma
    • 71. Chronic respiratory diseases: asthma, chronic obstructive pulmonary disease, post-tuberculosis lung disease, bronchiectasis and HIV lung disease
    • 72. The disabled patient
    • Part XI. Diseases of Body Systems:
    • 73. The heart
    • 74. The lung
    • 75. Blood disorders
    • 76. The gut
    • 77. The liver
    • 78. The kidney and body fluids
    • 79. Bones and joints
    • 80. Endocrinology
    • 81. The nervous system
    • 82. The skin
    • 83. The eye
    • 84. Ear, Nose and Throat (ENT)
    • Part XII. Cancer and Palliative Care:
    • 85. Approach to cancer care, the key role of palliative Medicine
    • 86. Approach to palliative care in cancer patients
    • 87. Common solid malignancies
    • 88. Common hematological malignancies
    • 89. Common childhood cancers
    • 90. Cancers in the HIV infected
    • Part XIII. Venoms and Poisons:
    • 91. Venomous and other dangerous animals
    • 92. Poisoning.
      Contributors
    • Yayehyirad Kitaw, Mitike Molla, Gail Davey, Eldryd Parry, Helen Nabwera, Modou Jobe, Andrew M. Prentice, Nathan Post, Kiran Jobanputra, Bern-Thomas Nyang'wa, Bukola Elizabeth Oluyide, Robert Onus, Bhargavi Rao, Heiner Grosskurth, Benson Droti, Juliet Nabyonga, Jean Baptiste Nikiema, Ruairi Brugha, Derrick Muneene, Tim Baker, Ben Morton, Karima Khalid, Mtisunge Kachingwe, Trustworthy Majuta, Camilla Buchanan, Peter Olute Okoth, Amha Achamyelew Yigzaw, Fabio Uxa, Helenlouise Taylor, Venice Omona, Giorgio Tamburlini, Anne J. Rerimoi, Ayo Palmer, E. Kim Mulholland, Martin W. Weber, Samuel Akech, Steve Collins, Marko Kerac, James A. Berkley, Bridget Freyne, Watipaso Wanda, Jenala Njirammadzi, Melita Gordon, Ambrose Agweyu, Heather Zar, Oghenebrume Wariri, Lien Anh Ha Do, Assan Jaye, Hilton C. Whittle, Rudzani Muloiwa, Gyaviira Nkurunungi, Gift Ahimbisibwe, Stephen Cose, Heidi Hopkins, Joaniter I. Nankabirwa, David Mabey, Christopher J. M. Whitty, Bayodé Roméo, Priscilla Haguma, Emmanuel Nsutebu, Sharon Nyesiga, Jamie Rylance, Shevin Jacob, Rodgers Ayebare, Daniel Bulwadda, Mohammed Lamorde, Titus Divala, Sam Ghebrehewet, Peter MacPherson, Sarah Staedke, Joaniter Nankabirwa, Arthur Mpimbaza, Abel Kakuru, Nyasha Veronica Dzavakwa, Sara Lowe, Rashida Ferrand, Linda Boloko, David Barr, Sean Wasserman, Charlotte Schutz, Graeme Meintjes, Stephen Gordon, Dingase Dula, Johnstone Kumwenda, Olubukola T. Idoko, Philippe Mayaud, Daniel J. McCartney, Francis J. Ndowa, David C. W. Mabey, Priyanka Patel, Esmeda Chirwa, Agness Lakudzala, Tom Parks, Frieder Schaumburg, Soumeya Ouangraoua, Mouhamadou Abdoulaye Sonko, Matthew P. Rubach, Elichilia R. Shao, Venance P. Maro, John Crump, Michael J. Maze, Georgies F. Mgode, Kajiru Kilonzo, John Crump, Geraint R. Davies, Robin Bailey, Richard Kock, Abdinasir Yusuf Osman, Leonard Mboera, Richard Idro, Charles R. Newton, Derek J. Sloan, Stellah G. Mpagama, Saba M. Lambert, Steve L. Walker, Richard Odame Phillips, Yaw Ampem Amoako, Samuel Duodu, Gloria Ansa, Japheth A. Opintan, Japheth A. Opintan, Appiah-Korang Labi, Noah Obeng-Nkrumah, Antoinette Bediako-Bowan, Emma Thompson, Catherine Houlihan, Naomi Walker, Stella Atim, Izabela Mauricio de Rezende, Derick Kimathi, George M. Warimwe, A. Desiree LaBeaud, Oyewale Tomori, Betty S. Apica, Geraldine A. O'Hara, Jolynne Mokaya , George M. Warimwe, Marieke Cornelia Johanna Dekker, Elichilia Robert Shao, Sarah Japhet Urasa, William Patrick Howlett, Nginache Nampota-Nkomba, Antonia Ho, Pascal Mkanda, Andrew Hall, Colin S. Brown, Olusola Aruna, Adesola Yinka-Ogunleye, Lance Turtle, Michael Abouyannis, Mainga Hamaluba, Michael Abouyannis, Mainga Hamaluba, Titus Divala, Michael Marks, Antonia Ho, Eduard Zijlstra, Ahmed M. Musa, Janelisa Musaya, Peter Nambala, Westain Tizgo Nyirenda, Julius Mulindwa, Eduard Zijlstra, Paul Kelly, Humphrey Mazigo, Michael Brown, Simon J Brooker, Stella Kepha, Amaya Bustinduy, Sekeleghe Kayuni, Ana Olga Mocumbi, Camilla Rothe, Linda B. Debrah, Samuel Wanji, Inge Kroidl, Michele Esther Murdoch, Ian Elliot Murdoch, Ewan Hunter, Sarah Urasa, Laura Nabarro, Karima Achour, Camilla Rothe, Clare E. Warrell, Anna M. Checkley, Chris Bodimeade, Rita Oladele, Olusola Ayanlowo, Bright Ocansey, Neil R. H. Stone, Yoseph Mamo, Andrew Mortimore, David I. W. Phillips, Jean Claude N. Mbanya, Camille M. Mba, Andrew E. Uloko, Roberta Lamptey, Geoffrey V. Gill, Richard W Walker, Matthew L. Davies, Kathleen Bateman, Tamara Phiri, Myles Connor, Alan Bryer, Laura Benjamin, Thembi Katangwe, Tiwonge Phiri, Macpherson Mallewa, Primrose Nyamayaro , Clement Nhunzvi, Rukudzo Mwamuka, Awoke Mihretu, Dixon Chibanda, Rebecca Nantanda, Duncan G. Fullerton, Kevin Mortimer, Refiloe Masekela, Brian Allwood, Stephen B. Gordon, Jeremiah Chakaya, Chris Lavy, Tracey Smythe, Debra Mudariki, Charles Kiiza Mondo , Juergen Freers, Twalib Aliku, Zhang Wanzhu, John G. Kellett, Jamie Rylance, Bruce Kirenga, I

    • Editors
    • David Mabey , London School of Hygiene and Tropical Medicine

      David Mabey is a physician specialising in Infectious and Tropical Diseases. He worked as a clinician in The Gambia for eight years before joining LSHTM, where he was head of the Clinical Research Department, Director of the Wellcome Trust Bloomsbury Centre for Clinical Tropical Medicine and Director of the WHO Collaborating centre for the Prevention and Control of Sexually Transmitted Infections. He chairs the Scientific and Technical Advisory Group of the WHO Department of Neglected Tropical Diseases and is a former president of the Royal Society of Tropical Medicine & Hygiene.

    • Martin W. Weber , World Health Organization

      Martin W. Weber is Team lead for Quality of Care, WHO Regional Office for Europe. He is a paediatrician who has been working for WHO for over twenty years in different continents, improving the care for mothers and children. He spent six years at the MRC labs in the Gambia where he was involved in the development and testing of clinical algorithms for newborn babies and children which became widely used as IMCI. He led the development of the Pocket book of children, a standard for clinical management in small hospitals widely translated and used for quality improvement in hospitals.

    • Moffat Nyirenda , London School of Hygiene and Tropical Medicine

      Moffat Nyirenda is a Diabetologist/Endocrinologist and Professor of Medicine (Global Non-Communicable Diseases) at the London School of Hygiene and Tropical Medicine (LSHTM), and leads the non-communicable disease research theme at MRC/UVRI and LSHTM Uganda Research Unit. He was among the first graduates from the College of Medicine in Malawi, with “hybrid” training between University College London and University of Malawi. He subsequently trained and worked at the University of Edinburgh, supported by a prestigious MRC Clinician Scientist Fellowship. Before taking up his current position at LSHTM in August 2013, he was Professor of Research at Malawi College of Medicine and Associate Director of Malawi-Liverpool-Wellcome Trust Clinical Research Programme. He is on the International Advisory Board for Davidson's principles and Practice of Medicine.

    • Dorothy Yeboah-Manu , Noguchi Memorial Institute for Medical Research, University of Ghana

      Dorothy Yeboah-Manu is a Professor of Microbiology and the Director, Noguchi Memorial Institute for Medical Research, University of Ghana. A major focus of her research is on tuberculosis and Buruli ulcer. She is a member of several local and international committees including the chairperson of the Advisory Board of the National Tuberculosis Program and the Vice President of the Immunological Society of Ghana. Dorothy Received the Royal Society Africa Prize in 2018 and a Senior Fellow of the EDCTP.

    • Jackson Orem , Uganda Cancer Institute, Kampala

      Jackson Orem is a medical oncologist and Executive Director of the Uganda Cancer Institute (UCI), a teaching and research institute of the Government of Uganda affiliated with Makerere University. He is currently spearheading the operationalization of the East Africa Centre of Excellence in Oncology (EACOE) at the Uganda Cancer Institute with the mandate of providing specialized cancer care research and training for the entire East Africa region under the East African Community (EAC) countries. He is also the alternate chair for African Cancer Coalition an initiative to improve management of cancer by harmonization of treatment practices in Sub-Saharan Africa.

    • Laura Benjamin , University College London

      Laura Benjamin is a Principal Research Fellow of Neurology at University College London and Honorary Consultant in Neurology at the National Hospital for Neurology and Neurosurgery, University College London Hospital. She has worked and lectured in East/Southern Africa with a particular focus on Neurological infection and stroke.

    • Michael Marks , London School of Hygiene and Tropical Medicine

      Michael Marks is an Associate Professor of Infectious Diseases at LSHTM and Honorary Consultant in Infectious Diseases at the Hospital for Tropical Diseases, University College London Hospital. He has worked in both the Pacific and West Africa with a particular focus on neglected tropical diseases and sexually transmitted infections.

    • Nicholas A. Feasey , Liverpool School of Tropical Medicine

      Nicholas A. Feasey is an Infectious Diseases physician and Professor of Clinical Microbiology at the Liverpool School of Tropical Medicine. He is based at the Malawi Liverpool Wellcome Research Programme, part of the Kamuzu University of Health Sciences in Blantyre, Malawi. His research is focused on the surveillance and management of antimicrobial resistant bacterial infection, and taking a one health approach to exploring the transmission of enteric pathogens associated with invasive disease, and he is a senior physician at Queen Elizabeth Central Hospital, Blantyre.